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    According to statistics, about 150 million men from 18 years and older suffer from problems in sexual life keeps its position.

    A physiological mechanism that ensures an erection is not possible without emitting of nitric oxide in cavernous body during sexual stimulation. NO activates a special enzyme called guanylate cyclase, as a result the level of cycle guanosine monophosphate cGMP is increased, muscles of the cavernous body relax and the blood flow is increased in a penis.


    Before beginning treatment, all patients were asked to measure IELT by using a stopwatch.


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    They recorded the average IELT in seconds from 3 consecutive separate occasions of intercourse. Data before and after treatment were compared using the paired t test for continuous data and chi-square test for categorical data.

    A power analysis was not conducted.


    Before beginning treatment, all patients were searched to measure IELT by laying a stopwatch.

    Therefore, the possibility of type II error exists with this sample size. In group 1, therapy was discontinued due to anejaculation in 2 patients and erectile dysfunction in 1 patient.

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  • There were no significant group means in mean orgasmic function, canada function, or sexual desire.
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  • In group 2, 5 patients did not return to complete the study. The mean age for patients in group 1 and group 2 was 30.

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    The mean duration of marriage for patients in group 1 and group 2 was 3. Treatment Effects Pretreatment Group Differences.


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    Table 1 contains the pretreatment means and standard deviations for the measures of IELT and the 5 categories of the IIEF-5 intercourse satisfaction, overall satisfaction, orgasmic function, erectile function, sexual desire and the probability of significant group differences.

    The mean IELTs were 70. These times are indicative of PE. Intragroup Effect of Drug Treatment. Table 2 contains the means and standard deviations of the outcome measures before and after receiving Hypericum extract and the probability of significant differences due to treatment.

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    After 4 weeks of treatment, the mean IELT had significantly increased from 70. There were no significant differences in orgasmic function or sexual desire. Two doses should Cecil Textbook of Medicine and Loeb.

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