Active Ingredient: Doxycycline
PLoS One. Published online Feb 25. Shaw Rachel E. Jacobs Byron C. Crump Amy R.
Received Oct 16; Accepted Jan 21. This article has been cited by other articles in PMC. Abstract Vibrio vulnificus and V. Vibrio illness originating from dermal contact with Vibrio laden waters or through ingestion of seafood originating from such waters can cause deleterious health effects, particularly if the strains involved are resistant to clinically important antibiotics.
Sonia ha degli amici che vede molto raramente: Damiano, Pietro ed il Moro.
Non avremmo potuto fare scelta migliore. Abbiamo cenato, su un tavolo di legno, con Roby, Ale e la Simy. Niente candele, ostriche e caviale... Immunopathologic damage was moderate to widespread in upper and lower reproductive-tract tissues from placebo- and doxycycline-treated monkeys but were significantly reduced in azithromycin-treated monkeys.
Azithromycin treatment dramatically reduced the inflammatory response and was highly effective in eradicating C.
As a result, effective treatment is often delayed, incomplete, or both. Several parenteral and oral treatment regimens are available for diagnosed PID.
However, the efficacy of these various regimens has not been well established. Currently, both azithromycin and doxycycline are recommended for the treatment of uncomplicated C.
The results of clinical trials have suggested that azithromycin and doxycycline are equally efficacious in the treatment of chlamydial cervical infection. However, human studies of the long-term sequelae of chlamydial upper reproductive-tract infection, including tubal fibrosis and adhesions, are limited.
Even more limited are human studies that have assessed the effects of azithromycin treatment in ameliorating upper reproductive-tract disease In the present study, we used the nonhuman primate model to establish acute chlamydial PID.
Briefly, the model has been used to establish and study C. We tested the efficacy of 2 antichlamydial antibiotics—doxycycline and azithromycin—on clearance of the microorganism after therapy, on reducing immunopathologic characteristics caused by C.
Prior approval for use of monkeys in this protocol was obtained from the Institutional Animal Care and Use Committee at the University of Washington.
Then, weekly for 5 weeks figure 1, the cervix was inoculated by cervical washes of a serovar E C.
The strain was originally isolated from the endometrium of a patient with PID.Published online Feb 25.