Active Ingredient: Doxycycline
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Never take an extra dose to make up for a forgotten one. You could also ask your pharmacist for advice on other ways to remember your medicines.
What if I take too much?
Accidentally taking an extra dose of doxycycline is unlikely to harm you. Speak to your pharmacist or doctor if you're worried or you take more than 1 extra dose.
Side effects Like all medicines, doxycycline can cause side effects, although not everyone gets them.
Common side effects These common side effects happen in around 1 in 10 people. Keep taking the medicine, but talk to your doctor or pharmacist if these side effects bother you or don't go away: headaches feeling or being sick nausea or vomiting being sensitive to sunlight Serious side effects are rare and happen in less than 1 in 1,000 people.
In rare cases, doxycycline can cause a serious allergic reaction anaphylaxis. These are not all the side effects of doxycycline.
For a full list see the leaflet inside your medicines packet. Information: You can report any suspected side effect to the UK safety scheme.
How to cope with side effects What to do about: headaches - make sure you rest and drink plenty of fluids. Everyday painkillers, such as paracetamol and ibuprofen, are safe to take with doxycycline.
Elaborate approaches led to the theory of signaling endosomes. Since then, spatial regulation of signal transduction has received more and more attention. Several reports focused on disease-related, mutant cytokine receptors and RTKs that show constitutive signaling.
Newly synthesized, intracellularly retained receptor is already able to signal. On the contrary, receptor at the plasma membrane and endocytosed receptor do not significantly contribute to constitutive activity.
Signals detected in non-treated cells are caused mainly by cellular autofluorescence.
Therefore, cell surface expression was analyzed by flow cytometry that is more sensitive than microscopy. Cells were fixed and receptor expression was analyzed by confocal microscopy.
The diagrams represent mCherry fluorescence intensities along the length of the white arrows.
Non-induced cells filled histograms were used as negative controls.